TABLE 2.
Antimicrobial susceptibilities of clinical isolates and transconjugants
| Strain no. (pI of ESBL in R+ strains)a | MIC (μg/ml)
|
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ampicillin | Piperacillin | Piperacillin + tazobactam |
Cefotaxime | Cefotaxime + clavulanate |
Cefotaxime + tazobactam |
Ceftazidime | Ceftazidime + clavulanate |
Ceftazidime + tazobactam |
Aztreonam | Aztreonam + clavulanate |
Aztreonam + tazobactam |
Cefoxitin | Imipenem | |
| K. pneumoniae | ||||||||||||||
| L-267 | >512 | >512 | 8 | 32 | 0.25 | 0.25 | 128 | 0.5 | 0.5 | 128 | 0.125 | 0.25 | 16 | 0.125 |
| L-372 | >512 | >512 | 8 | 8 | 0.125 | 0.125 | 64 | 0.5 | 0.5 | 64 | 0.25 | 0.25 | 4 | 0.125 |
| L-380 | >512 | >512 | 8 | 8 | 0.125 | 0.125 | 64 | 0.5 | 0.5 | 64 | 0.25 | 0.25 | 4 | 0.125 |
| L-491 | >512 | >512 | 8 | 16 | 0.25 | 0.25 | 128 | 0.5 | 0.5 | 128 | 0.25 | 0.25 | 8 | 0.25 |
| L-577 | >512 | >512 | 8 | 8 | 0.125 | 0.125 | 128 | 0.5 | 0.5 | 128 | 0.25 | 0.25 | 8 | 0.125 |
| L-439 | >512 | >512 | 4 | 32 | 0.25 | 0.25 | 128 | 0.5 | 0.5 | 128 | 0.125 | 0.25 | 2 | 0.25 |
| L-414 | >512 | >512 | 4 | 16 | 0.06 | 0.06 | 128 | 0.5 | 0.5 | 256 | 0.125 | 0.5 | 2 | 0.125 |
| L-251 | >512 | >512 | 8 | 32 | 0.06 | 0.5 | 512 | 1 | 2 | 512 | 0.125 | 0.5 | 8 | 0.125 |
| L-95 | >512 | >512 | 16 | 32 | 0.125 | 0.5 | 512 | 2 | 8 | 512 | 0.125 | 4 | 8 | 0.125 |
| L-352 | >512 | 512 | 4 | 16 | 0.125 | 0.5 | 256 | 1 | 1 | 256 | 0.06 | 0.25 | 4 | 0.25 |
| L-902 | >512 | >512 | 16 | 64 | 0.125 | 0.5 | 512 | 2 | 8 | 512 | 0.25 | 2 | 8 | 0.125 |
| E. coli L-867 | >512 | >512 | 16 | 64 | 16 | 4 | 64 | 16 | 8 | 128 | 8 | 8 | 64 | 0.125 |
| Transconjugants | ||||||||||||||
| R+ L-267 (6.0) | >512 | 256 | 0.5 | 8 | ≤0.03 | ≤0.03 | 32 | 0.125 | 0.125 | 32 | 0.06 | 0.06 | 2 | 0.25 |
| R+ L-372 (6.0) | >512 | 256 | 0.5 | 8 | ≤0.03 | 0.06 | 16 | 0.125 | 0.125 | 32 | 0.06 | 0.06 | 2 | 0.25 |
| R+ L-380 (6.0) | >512 | 512 | 0.5 | 16 | ≤0.03 | ≤0.03 | 32 | 0.125 | 0.125 | 64 | 0.06 | 0.06 | 2 | 0.25 |
| R+ L-491 (6.0) | >512 | 256 | 0.5 | 8 | ≤0.03 | ≤0.03 | 16 | 0.125 | 0.125 | 32 | 0.06 | 0.06 | 4 | 0.25 |
| R+ L-577 (6.0) | >512 | 256 | 0.5 | 8 | ≤0.03 | ≤0.03 | 16 | 0.125 | 0.125 | 32 | 0.06 | 0.06 | 2 | 0.25 |
| R+ L-439 (8.2) | 256 | 32 | 1 | 2 | ≤0.03 | ≤0.03 | 16 | 0.06 | 0.125 | 32 | 0.06 | 0.06 | 2 | 0.25 |
| R+ L-414 (8.2) | 256 | 32 | 1 | 2 | ≤0.03 | ≤0.03 | 16 | 0.06 | 0.125 | 32 | ≤0.03 | ≤0.03 | 2 | 0.25 |
| R+ L-251 (8.2) | 512 | 64 | 0.5 | 4 | ≤0.03 | ≤0.03 | 32 | 0.06 | 0.125 | 64 | 0.06 | 0.06 | 2 | 0.25 |
| R+ L-867 (6.0) | >512 | 128 | 0.5 | 2 | ≤0.03 | ≤0.03 | 16 | 0.06 | 0.125 | 32 | 0.06 | ≤0.03 | 2 | 0.25 |
| E. coli A15 (recipient) | 2 | 0.5 | 0.5 | ≤0.03 | ≤0.03 | ≤0.03 | 0.06 | 0.06 | 0.06 | 0.06 | ≤0.03 | ≤0.03 | 2 | 0.25 |
a
R+, transconjugants.