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Stimulation of vector production by sodium butyrate. Vectors derived from either pCMV-HIV-1 or pCHGP-2 were generated in 293T cells in the presence of various concentrations of sodium butyrate as indicated. Titers were determined in HT1080 cells as described in Materials and Methods. Values are the ratios of titers with sodium butyrate to titers without sodium butyrate for each vector. This experiment was repeated once, and similar results were obtained (data not shown).
