FIG. 2.
Alternative structures of RBE concatemers. (a) Design of an RBE hexamer by Kjems and Sharp (29). The desired structure is shown. Rev protein molecules interacting with the internal loop of the RBE are again represented as oblongs. (b) Predicted secondary structure of the RBE hexamer. When the secondary structure of the RBE hexamer shown in panel a is modeled with the program Mulfold (24, 25, 60), an elongated RNA originally predicted by Zemmel et al. (58) is observed.

