Figure 3.
Diagrammatic representation of the regulatory systems for Aβ in an AD patient’s brain. Aβ, amyloid-beta; BBB, Blood–brain barrier; RAGE, Receptor for advanced glycation end products; AICD, APP intracellular C-terminal domain; APP, Amyloid precursor protein; ApoE, apolipoprotein E; E4, ApoE; E3, ApoE3; E2, ApoE2. Created with BioRender.com.
